A five year audit of the role of parathyroid hormone assays and thallium-technetium isotope subtraction scanning in the preoperative investigation of primary hyperparathyroidism.
نویسندگان
چکیده
An audit has been performed of the value of parathyroid hormone assays and thallium-technetium isotope scanning in the pre-operative investigation of 67 hypercalcaemic patients referred for surgery over a 5 year period. Parathyroid hormone assay by region-specific technique was found to have a diagnostic sensitivity of 75% (n = 52) whilst the more recent assay for the intact molecule was 97% sensitive (n = 34). Thallium-technetium isotope scanning was only 64% sensitive overall (n = 59), due in part to the small size of adenomata now being referred for surgery. This study confirms the role of the intact parathyroid hormone assay but questions that of thallium-technetium isotope scanning in standard protocols of investigation for hypercalcaemia.
منابع مشابه
A five year audit of the role of parathyroid hormone assays and thallium-technetium isotope subtraction scanning
An audit has been performed of the value of parathyroid hormone assays and thallium-technetium isotope scanning in the pre-operative investigation of 67 hypercalcaemic patients referred for surgery over a 5 year period. Parathyroid hormone assay by region-specific technique was found to have a diagnostic sensitivity of75% (n = 52) whilst the more recent assay for the intact molecule was 97% sen...
متن کاملSensitivity and specificity of thallium-technetium subtraction scan in localization of the parathyroid adenoma [Persian]
Thirty one patients with biologic and clinical diagnosis of hyperparathyroidism were submitted to thalium-technetium scan prior to exploration of the neck. Scan findings were compared with the pathologic results. Surgical exploration of the neck showed a parathyroid adenoma in 24 patients, parathyroid carcinoma in one patient, normal parathyroid in another patient and parathyroid hyperplasia in...
متن کاملRadionuclide techniques in the diagnosis of primary hyperparathyroidism. The role of technetium 99m--thallium 201 subtraction scanning.
The role of various radionuclide investigations, including parathyroid scintigraphy, bone scintigraphy and serum parathormone estimations in the diagnosis of primary hyperparathyroidism is reviewed briefly. The initial experience with the dual isotope (Tl-201; Tc-99m) subtraction scintigraphy for the preoperative localization of parathyroid adenomas is presented (JPMA 37 : 237, 1987).
متن کاملThallium-technetium isotope subtraction imaging of parathyroid for localization of transplanted parathyroid tissue after the surgery [Persian]
Abstract is NOT available
متن کاملبررسی 110 مورد هیپرپاراتیروئیدی اولیه در بیمارستان دکتر شریعتی و نتایج لوکالیزاسیون آدنوم توسط اسکن MIBI
Primary Hyperparathyroidism is a fairly common disease that is much more predominant in females. Treatment is surgery and includes removing the parathyroid adenoma or the hyperplastic parathyroid glands. Considering the difficulty of this operation procedure, localization test are utilized including ultrasound, MRI, CT scan, Thallium-Technesium subtraction scan, MIBI scan and a series of other ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Postgraduate medical journal
دوره 67 794 شماره
صفحات -
تاریخ انتشار 1991